• Efficient mesoscale phenotypic screening in cultured primary neuron culture Nedrud D., He Y., Schmidt D. bioRxiv

  • Domain insertion permissibility-guided engineering of allostery in ion channels Coyote-Maestas W., He Y., Myers C.L., Schmidt D. Nature Communications 2019 10:290, doi: 10.1038/s41467-018-08171-0

  • Combinatorial Assembly of Lumitoxins Nedrud D., Schmidt D. Methods in Molecular Biology doi: 10.1007/978-1-4939-7362-0_15

  • A fully genetically encoded protein architecture for optical control of peptide ligand concentration. Schmidt D., Tillberg P.W., Chen F., Boyden E.S. Nature Communications 2014 4:3019, doi: 10.1038/ncomms4019

  • Mechanistic basis for low threshold mechanosensitivity in voltage-dependent K+ channels. Schmidt D., del Mármol J., MacKinnon R. Proc Natl Acad Sci U S A 2012 Jun 26;109(26):10352-7. doi: 10.1073/pnas.1204700109.

  • Measuring cation dependent DNA polymerase fidelity landscapes by deep sequencing. Zamft, B.M., Marblestone, A.H., Kording, K., Schmidt, D., Martin-Alarcon, D., Tyo, K., Boyden, E.S., and Church, G. PLoS ONE 7, e43876 (2012).

  • Functional Reconstitution of a Voltage-Gated Potassium Channel in Giant Uni- lamellar Vesicles. Aimon S., Manzi J., Schmidt D., Poveda Larrosa J.A., Bassereau P., Tombes G.E.S. PLoS ONE 6(10): e25529 (2011).

  • Voltage-dependent K+ channel gating and voltage sensor toxin sensitivity depend on the mechanical state of the lipid membrane. Schmidt D., MacKinnon R. Proc Natl Acad Sci U S A 2008 Dec 9;105(49):19276-81. doi: 10.1073/pnas.0810187105.

  • A gating model for the archeal voltage-dependent K(+) channel KvAP in DPhPC and POPE:POPG decane lipid bilayers. Schmidt D., Cross SR, MacKinnon R. J Mol Biol 2009 Jul 31;390(5):902-12. doi: 10.1016/j.jmb.2009.05.062.

  • Phospholipids and the origin of cationic gating charges in voltage sensors. Schmidt D., Jiang QX, MacKinnon R. Nature 2006 Dec 7;444(7120):775-9.

  • Homodimerization of the G protein SR-beta in the nucleotide-free state controlled by proline cis/trans isomerization in the switch II region. Schwartz T.U., Schmidt D., Brohawn S.G., Blobel G. (2006). Proc Natl Acad Sci U S A 103(18):6823-8

  • The beta-subunit of the protein-conducting channel of the endoplasmic reticulum functions as the guanine nucleotide exchange factor for the beta-subunit of the signal recognition particle receptor. Helmers J., Schmidt D., Glavy J.S., Blobel G., Schwartz T.U. (2003). J Biol Chem 278(26): 23686-90


  • Natural photoreceptors and their application to synthetic biology Schmidt, D. & Cho, Y.K. (2014) Trends Biotechnol